Clino-Pathological Study of Human Onchocerciasis In Imo River Basin, Nigeria, and Its Implication To The Controlof The Disease In The Area.
In a two year study of human onchocerciais in Imo River Basin, 1716 (75.3%) of 2278 individuals examined for various clinical signs of onchocerciasis haboured one or more onchocercal lesions. The commonest lesion encountered was nodules (20. 7) followed by leopard skin (19.3%). while hydrocele/elephantiasis were the . least (2.4%). Prevalence of clinical signs varied with sex and age gro_lJps, with males and adults recording significantly (P<0.05) higher manifestations than females and adolescence. Onchocerciasis endemicity as measured by the prevalence of palpable nodules was high (20.7%). The prevalence of microfilaries was fairly high (49.4%) while the intensity was generally low. Microfilarial rate tallied significantly (P<0.05) and positively with the prevalence of nodules, leopard skin, pruritus, blindness and musculo-skeletal pain .in the communities surveyed. The epidemiological significance of this study in terms of a more comprehensive health education of the masses and a highly supervised ivermectin distribution for the control of the disease is highlighted.