Publisher: Bachudo Science Co. Ltd

Studies On Certain Characteristics of Extracts of Bark of Pausinystalia Johimbe and Pausinystalia Macroceras (K.SCHUM.) Pierre Ex Beille

Oluwole A. Sodipo, Josephine V. Ogunbameru
KEYWORDS: Saponins, Pausinystalia johiinbe, P. macroceras, bark extracts.

ABSTRACT:

Phytochemical screening revealed the probable presence of alkaloids, saponins, phlobatannins, anthrequinones, coumarins and cardiac glycosides in the bark of two species of Pausinystalia (P. macrocerns and P. johimbe) .  Besides, the results also showed that while tannins and combined anthraquinones were probably present in P. johimbe, the same extract of P. macroceras was probably devoid of them. Extracts, phosphate buffered saline (PBS) and methanol/phosphate buffered saline (M/PBS) of the same sample were also screened for potential haemolytic activity. The results showed that the two extracts were haemolytic'with human red bloo.d. cells. However, generally the haemolytic activities of the M/PBS extracts of the two species of plant were higher than those of PBS extracts, using the var.los types of blood groups (0,A,B,AB). The foamability of the extracts was also investigated. The results showed that PBS extracts of P. macroceras and P. johimbe_produced long-lasting foams of 67.39 ± 9.03 hr and 32.55 ± 4.44 hr respectively. Moreover, while the M/PBS extract of P. johimbe produced a long-lasting foam of 283.4 ± 8.49 hr, that of P. macroceras was· only 0.11 ± 0.01 hr.. The results have been discussed with respect to the probable presence of saponins in the samples. The potentials of this class of secondary metabolites of plant origin in medicine pharmaceutical industry and technology have also been highlighted.


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