Publisher: Bachudo Science Co. Ltd

Effect of Aqueous Extract (CRUDE) of Leaves of Vernonia Amygdalina (DEL) On Blood Glucose, Serum Albumin and Cholesterol Levels In Diabetic Albino Rats.

F. O. Uhegbu, Kingsley J. Ogbuehi
KEYWORDS: Blood glucose, serum albumin, Cholesterol, hypoglycemic, antilipolytic and lipogenic effects

ABSTRACT:

Effect of crude aqueous extract of leaves of Vernonia amygdalina on blood glucose, serum albumin and cholesterol levels on alloxan induced diabetic albino rats was investigated. Blood glucose, serum albumin and cholesterol levels WEire significantly reduced. From 296.75 ± 9.0mg/dl to 179.0 ± 7.3mg/dl for blood glucose; 4.08 ± 0.4mg/dl to 0.93 ± 0.23mg/dl for serum albumin, while cholesterol level decreased from 280.33 ± 4.65mg/dl to 170.45 ± 4.52mg/dl. The effect was dose dependent, as the reduction followed increase in dose given to the animals. The biochemical implication of our findings are discussed.  


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