Publisher: Bachudo Science Co. Ltd

Correlations Between Antibiotic Intake and Resistance of Some Enteric Gram Negative Bacilli To Antibiotics

E. A. Eze, I. M. Ezeonu, J. I. Okafor
KEYWORDS: Human population, Drug intake, Enteric bacteria, Drug resistance, Resistance correlation.

ABSTRACT:

Some enteric Gram negative bacteria were isolated over a three – year (2006 – 2008) period from two human populations designated as population on therapy (OD) and population not on therapy (ND). Isolates were analyzed for susceptibility to a panel of ten antibacterial agents. Results showed that OD isolates were generally more resistant to test drugs than ND isolates but the differences were not significant at both 0.01 and 0.05 levels. Pearson correlation analysis showed that the correlation in resistances among the OD and ND isolates was systematic and significant at both 0.01 and 0.05 levels, suggesting that resistance emergence and sustenance may not be an exclusive consequence of intake and misuse of antibiotics.


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