Publisher: Chemical Society of Nigeria

Phytochemical and Antibacterial Screening of The Extracts of The Stem Bark of Ficus Platyphylla

I. Y. Chindo,, H. M. Adamu, K. S. Gamaniel
KEYWORDS: Percent recovery, phytochemical, antibacterial and Ficus platyphylla

ABSTRACT:

Air-dried pulverized bark sample of Ficus platyphylla were extracted by polarity guided approach with hexane, toluene, ethyl acetate, ethanol and water using both cold and hot solvent extraction methods. Ethanol gave the highest percent recovery of extracts, 37 % and 41.5 % for hot and cold extractions respectively. The least percent recovery of 0.1 % and 1.5 % were obtained for the hot and cold methods respectively using toluene. The phytochemical screening of these extracts revealed the presence of alkaloids, tannins, cardiac glycosides, and flavonoids with a strong presence of saponin in the ethanol extracts. All the test organisms were sensitive to the extracts at concentrations of 250 μg/ml and 150 μg/ml and resistant at 50 μg/ml and below. The hot ethylacetate extract gave the least MIC, 100 μg/ml against Staphylococcus aureus, while water extracts showed the highest MIC, 250 μg/ml against all test bacterial organisms.


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